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The first Generative Foundation Model for RNA design. Unifying the RNA world through advanced AI technology.

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Developed by researchers from

Xi'an Jiaotong University

Fudan University

Shanghai AI Laboratory

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siRNA Design

Therapeutic RNA

Small interfering RNA for targeted gene silencing & RNA interference therapy.

Generate RNA sequence from scratch

Prompt Sequence (optional)

0 / 10,000A, U, G, C

Species (optional)

Max Length200

Research Highlights

Published examples and benchmark results for siRNA design.

Paper Examples

PCSK9 siRNA

Clinically validated siRNA targeting PCSK9 for cholesterol reduction.

GCAAGAAUCCUGAUUGAAATT

Homo sapiensNEJM 2024

Benchmark Results

Efficiency

93%

Gene Knockdown

Superior gene silencing compared to conventional design tools.

View paper

Specificity

0.98

Off-target Score

Minimal off-target effects with optimized seed regions.

View paper

Exploring EVA...

Back to Home

siRNA Design

Therapeutic RNA

Small interfering RNA for targeted gene silencing & RNA interference therapy.

Generate RNA sequence from scratch

Prompt Sequence (optional)

0 / 10,000A, U, G, C

Species (optional)

Max Length200

Research Highlights

Published examples and benchmark results for siRNA design.

Paper Examples

PCSK9 siRNA

Clinically validated siRNA targeting PCSK9 for cholesterol reduction.

GCAAGAAUCCUGAUUGAAATT

Homo sapiensNEJM 2024

Benchmark Results

Efficiency

93%

Gene Knockdown

Superior gene silencing compared to conventional design tools.

View paper

Specificity

0.98

Off-target Score

Minimal off-target effects with optimized seed regions.

View paper