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The first Generative Foundation Model for RNA design. Unifying the RNA world through advanced AI technology.

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Developed by researchers from

Xi'an Jiaotong University

Fudan University

Shanghai AI Laboratory

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CircRNA Design

Circular RNA

Circular RNA engineering for stable expression, vaccine platforms & sponge design.

Generate RNA sequence from scratch

Prompt Sequence (optional)

0 / 10,000A, U, G, C

Species (optional)

Max Length200

Research Highlights

Published examples and benchmark results for circRNA design.

Paper Examples

circRNA Vaccine Scaffold

Circular RNA scaffold for enhanced antigen presentation.

AUGCGAUUCGAACGUAACGCUUAGCGUAGCUAGCGAUUCGAACGUAACGCUUAGCGUAGCUAGCGAUUCGAACGUAACGCUUAGCGUAGCU

Homo sapiensCell 2024

miRNA Sponge circRNA

Engineered circRNA sponge for competitive miRNA binding.

AUGCUAGCUAGCUAGCUAGCUAGCUAGCUAGCUAGCUAGCUAGCUAGCUAGC

Homo sapiensMol. Cell 2023

Benchmark Results

Stability

72h

Expression Duration

Sustained protein expression from circular RNA constructs.

View paper

Efficiency

90%

Circularization

High-efficiency circularization with optimized splice sites.

View paper

Exploring EVA...

Back to Home

CircRNA Design

Circular RNA

Circular RNA engineering for stable expression, vaccine platforms & sponge design.

Generate RNA sequence from scratch

Prompt Sequence (optional)

0 / 10,000A, U, G, C

Species (optional)

Max Length200

Research Highlights

Published examples and benchmark results for circRNA design.

Paper Examples

circRNA Vaccine Scaffold

Circular RNA scaffold for enhanced antigen presentation.

AUGCGAUUCGAACGUAACGCUUAGCGUAGCUAGCGAUUCGAACGUAACGCUUAGCGUAGCUAGCGAUUCGAACGUAACGCUUAGCGUAGCU

Homo sapiensCell 2024

miRNA Sponge circRNA

Engineered circRNA sponge for competitive miRNA binding.

AUGCUAGCUAGCUAGCUAGCUAGCUAGCUAGCUAGCUAGCUAGCUAGCUAGC

Homo sapiensMol. Cell 2023

Benchmark Results

Stability

72h

Expression Duration

Sustained protein expression from circular RNA constructs.

View paper

Efficiency

90%

Circularization

High-efficiency circularization with optimized splice sites.

View paper